SEMINAIRE Mulhousien de MATHEMATIQUES

résumé/abstract


Richard Kerner (LPTMC, Paris)

Symmetries, classification and evolutionary trends of icosahedral viral capsids

 

A classification of icosahedral viral capsids is proposed. We show how the self-organization of capsids during their production implies a definite composition of their elementary building blocks. The exact number of hexamers with three different admissible symmetries is related to capsids' sizes, labeled by their  T-numbers. Simple rules determining these numbers for each value of  T are deduced and certain consequences concerning the probabilities of mutations and evolution of capsid viruses are discussed.

 


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Dernières modifications / Last modifications :  21 Mai 2008